Depression: Essential Facts You Need to Know

Depression is a pervasive and serious mental health condition that affects millions of people worldwide. Despite its prevalence, it is often misunderstood and stigmatized. Here, we visit the essential facts about this condition; its symptoms, diagnosis, and effective treatment options.

Prevalence and Impact

Depression is a leading cause of disability, profoundly affecting individuals’ physical, emotional, and social well-being across the globe. It not only diminishes quality of life but also disrupts daily functioning, making it difficult for those affected to carry out basic tasks such as working, maintaining relationships, and engaging in self-care.

Notably, depression tends to affect women at higher rates than men, a pattern observed across various cultures and regions. Several factors may contribute to this gender disparity, including biological differences, hormonal fluctuations, and societal pressures that disproportionately affect women, such as caregiving responsibilities and gender-based violence. Additionally, young adults aged 18-25 years have the highest prevalence. and among adolescents, the numbers are even more concerning.

This period of life often involves significant transitions, such as entering the workforce, pursuing higher education, and developing new relationships, which can trigger or exacerbate mental health issues. For adolescents, the situation is even more concerning. Studies indicate that rising numbers of teens are struggling with depression, partly due to the pressures of social media, academic stress, and other socio-environmental factors. Left untreated, depression in these formative years can lead to long-term negative outcomes, including increased risk for substance abuse, suicide, and other mental health disorders.

How Can You Recognize Depression – Symptoms and Signs?

The condition can manifest in various ways in different individuals.

  • Persistent Depressed Mood: A constant feeling of sadness or irritability, especially in children and adolescents.
  • Anhedonia: A marked loss of interest or pleasure in most activities.
  • Changes in Appetite or Weight: Significant weight loss or gain, or changes in appetite.
  • Sleep Disturbances: Insomnia or excessive sleeping.
  • Psychomotor Changes: Noticeable agitation or retardation in movement.
  • Fatigue: Persistent tiredness or lack of energy.
  • Feelings of Worthlessness: Excessive or inappropriate guilt.
  • Cognitive Difficulties: Trouble concentrating, making decisions, or thinking clearly.
  • Suicidal Thoughts: Recurrent thoughts of death or suicide, or specific plans for committing suicide.

For a diagnosis of major depressive disorder, at least five of these symptoms must be present for two weeks, with at least one being either depressed mood or anhedonia.

Diagnostic Tools and Screening

Several screening tools can aid in diagnosing depression:

  • Patient Health Questionnaire-9 (PHQ-9): A 9-item self-report scale that scores the severity of depression.
  • Beck Depression Inventory (BDI): A 21-question self-report scale.
  • Hamilton Depression Rating Scale (HDRS): Administered by a healthcare professional, this scale helps assess the severity of depression.

While these tools are helpful, a comprehensive clinical evaluation by a healthcare provider is essential for an accurate diagnosis.

Treatment Options

Effective treatment for depression often involves a combination of medication and psychotherapy. Here are some key approaches:

Medicines: Common medications include:

  • Selective Serotonin Reuptake Inhibitors (SSRIs): Such as fluoxetine and sertraline.
  • Serotonin-Norepinephrine Reuptake Inhibitors (SNRIs): Like venlafaxine and duloxetine.
  • Atypical Antidepressants: Such as bupropion.
  • Tricyclic Antidepressants (TCAs): An older class of medications.
  • Monoamine Oxidase Inhibitors (MAOIs): Typically used when other treatments are ineffective.

Psychotherapy: Evidence-based therapies include:

  • Cognitive Behavioral Therapy (CBT): Helps patients identify and change negative thought patterns.
  • Interpersonal Therapy (IPT): Focuses on improving interpersonal relationships.
  • Behavior Therapy: Emphasizes changing harmful behaviors.

Other Treatments:

  • Electroconvulsive Therapy (ECT): Effective for severe depression or when other treatments have failed.
  • Transcranial Magnetic Stimulation (TMS): FDA-approved for treatment-resistant depression.
  • Vagus Nerve Stimulation (VNS): Used for patients not responding to multiple treatments.

Importance of Early Intervention

Early recognition and treatment of depression are important for improving outcomes. Help should be sought when symptoms of depression are experienced by an individual or observed in a close relation or associate.

Conclusion

Depression is a complex but treatable condition. Recognizing its symptoms and promptly seeking help and treatment strategies can significantly improve the lives of those affected.

Do not hesitate to reach out to us by booking an appointment to speak to a therapist if you feel any of these signs.

This article was written by Dr. Olalekan Kolawole, MBBS, and reviewed by Cynthia A. Puchammer, LCSW